Cancer (Tumor) Cell Lines
Mus musculus (Mouse)
Breast (mammary gland)
Adherent
4T1 is a mouse breast cancer cell line, established from a malignant neoplasm of the mouse mammary gland. The 4T1 cells are tumorigenic and highly metastatic. The transplantable tumor can spontaneously metastasize from the primary site to multiple tissues, including the lymph nodes, blood, liver, lung, brain, and bone. This progressive process of tumor growth and metastatic spread of 4T1 cells closely mimics human breast cancer; therefore, this cell line is regarded as an animal model of stage IV human breast cancer for studying breast cancer progression, immune response, and metastasis.
Synonym: 4T1-A; 4T1.0; 4T1/WT
B. A. Pulaski and S. Ostrand‐Rosenberg, “Mouse 4T1 Breast Tumor Model,” CP in Immunology, vol. 39, no. 1, Oct. 2000, doi: 10.1002/0471142735.im2002s39.
ESYT1 Knockout K562 Polyclonal Cells
Cat. No. ARG19378
NR4A1 Knockout HEK293 Polyclonal Cells
Cat. No. ARG12724
NRG4 Knockout CAL27 Polyclonal Cells
Cat. No. ARG11512
BICD2 Knockout A549 Polyclonal Cells
Cat. No. ARG31939
FPGT Knockout A549 Polyclonal Cells
Cat. No. ARG9945
FXR2 Knockout AGS Polyclonal Cells
Cat. No. ARG2748
Complete description is available upon request.
