Immortalized Cell Line
Kidney
Adherent
M-1 cells are derived from the normal kidney tissue of tg(SV40E)Bri7 transgenic mice and contain integrated SV40 viral DNA. They keep some common characteristics with the cells of the cortical collecting duct (CCD), including typical morphology and expression of CCD-specific antigens. Otherwise, most M-1 cells exhibit features of either intercalated cells or principal cells, the two major cell types of the cortical collecting duct. A subset of 5–10% of the population displays a mixed phenotype, expressing markers of both cell types. When cultured on permeable supports, M-1 cells are capable of forming cavity-like structures and exhibit a measurable negative transepithelial potential difference, indicative of functional polarization.
P4HA2 Knockout NCI-H1975 Polyclonal Cells
Cat. No. ARG17288
METTL13 Knockout SK-HEP-1 Polyclonal Cells
Cat. No. ARG16294
NTN1 Knockout SK-Hep-1 Polyclonal Cells
Cat. No. ARG16244
KAT6B Knockout Hela Polyclonal Cells
Cat. No. ARG26333
GYPC Knockout A2780 Polyclonal Cells
Cat. No. ARG29095
AVL9 Knockout A549 Polyclonal Cells
Cat. No. ARG31902
Complete description is available upon request.