Finite Cell Lines
Macaca fascicularis (Cynomolgus Monkey)
Skin
Adherent
CYNOM-K1 is a skin fibroblast finite cell line derived from a a Cynomologus monkey embryo. Cynomolgus Monkey (Macaca fascicularis) is also commonly known as the long-tailed macaque or crab-eating macaque. In in vitro transformation assay and in vivo tumorigenic evaluation, CYNOM-K1 cells exhibited free of any tumorigenic characteristics. In the test of poliovirus replication, the CYNOM-K1 cell line was permissive to the growth of Sabin poliovirus types 1, 2, and 3, which made it a significant cell model for research and development of poliovirus vaccine.
Synonym: Cynom-K1; CYNOMK-1; CYNOMK1; CYNOM-1
Dotti S, Lombardo T, Villa R, et al. Transformation and Tumorigenicity Testing of Simian Cell Lines and Evaluation of Poliovirus Replication. PLoS One. 2017;12(1):e0169391. Published 2017 Jan 3. doi:10.1371/journal.pone.0169391
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Complete description is available upon request.
