Cancer (Tumor) Cell Lines
Homo sapiens (Human)
Breast (mammary gland)
Adherent
MDA-MB-436 is a human triple-negative breast cancer (TNBC) cell line, which means that it lacks estrogen receptor (ER) and progesterone receptor (PR) expression, as well as HER2 (human epidermal growth factor receptor 2) amplification. MDA-MB-436 cells has mutations in BRCA1 and TP53, which are related to the regulation of DNA repair. This makes MDA-MB-436 a useful tools to investigate BRCA1 and TP53 associated tumorigenesis.
Synonym: MDA_MB_436; MDA MB 436; MDA-Mb-436; MDA-MB436; MDAMB436; MDA-436; MDA436; MB436
NPC1 Knockout A2780 Polyclonal Cells
Cat. No. ARG18536
CPEB2 Knockout NCI-H1975 Polyclonal Cells
Cat. No. ARG16842
PHF6 Knockout jurkat Polyclonal Cells
Cat. No. ARG13128
ARHGAP36 Knockout FTC-133 Polyclonal Cells
Cat. No. ARG28517
ATG7 Knockout NCI-H1975 Polyclonal Cells
Cat. No. ARG31246
HDAC6 Knockout HGC-27 Polyclonal Cells
Cat. No. ARG36128
Complete description is available upon request.