Cancer (Tumor) Cell Lines
Homo sapiens (Human)
Breast (mammary gland)
Adherent
MDA-MB-436 is a human triple-negative breast cancer (TNBC) cell line, which means that it lacks estrogen receptor (ER) and progesterone receptor (PR) expression, as well as HER2 (human epidermal growth factor receptor 2) amplification. MDA-MB-436 cells has mutations in BRCA1 and TP53, which are related to the regulation of DNA repair. This makes MDA-MB-436 a useful tools to investigate BRCA1 and TP53 associated tumorigenesis.
Synonym: MDA_MB_436; MDA MB 436; MDA-Mb-436; MDA-MB436; MDAMB436; MDA-436; MDA436; MB436
MGRN1 Knockout SK-HEP-1 Polyclonal Cells
Cat. No. ARG16070
AGFG1 Knockout HAP1 Polyclonal Cells
Cat. No. ARG27224
ARHGEF28 Knockout A549 Polyclonal Cells
Cat. No. ARG31620
CALD1 Knockout SK-HEP-1 Polyclonal Cells
Cat. No. ARG41838
PCIF1 Knockout HEK293T Polyclonal Cells
Cat. No. ARG4349
Rat Gingival Fibroblasts
Cat. No. ARP0402
Complete description is available upon request.
