Primary Cells
Homo sapiens (Human)
Joint (synovium)
Adherent
Human fibroblast-like synoviocytes (FLS) from adult osteoarthritis donors are freshly isolated from synovial tissue of a donor with arthritic disease. These cells, also known as synovial fibroblasts or type B synoviocytes, are specialized stromal cells that line the synovium and are responsible for producing extracellular matrix components and synovial fluid. In osteoarthritis, FLS exhibit altered phenotypes, including increased production of inflammatory mediators and matrix-degrading enzymes. Therefore, they are widely used as in vitro models to study joint inflammation, cartilage degradation, and the molecular mechanisms underlying osteoarthritis progression.
HP1BP3 Knockout MES-OV Polyclonal Cells
Cat. No. ARG24566
ALOX12 Knockout KYSE150 Polyclonal Cells
Cat. No. ARG36207
MMP8 Knockout KYSE30 Polyclonal Cells
Cat. No. ARG9722
CHEK1 Knockout THP-1 Polyclonal Cells
Cat. No. ARG7348
DBNL Knockout HEK293T Polyclonal Cells
Cat. No. ARG4130
MAPK8IP3 Knockout AGS Polyclonal Cells
Cat. No. ARG2637
Complete description is available upon request.