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4T1 | ovaryresearch.com

4T1

Product Type:
Cancer (Tumor) Cell Lines
Tissue Source:
Breast (mammary gland)
Disease:
Malignant neoplasm
Species:
Mus musculus (Mouse)
$1,300.00
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4T1 is a mouse breast cancer cell line, established from a malignant neoplasm of the mouse mammary gland. The 4T1 cells are tumorigenic and highly metastatic. The transplantable tumor can spontaneously metastasize from the primary site to multiple tissues, including the lymph nodes, blood, liver, lung, brain, and bone. This progressive process of tumor growth and metastatic spread of 4T1 cells closely mimics human breast cancer; therefore, this cell line is regarded as an animal model of stage IV human breast cancer for studying breast cancer progression, immune response, and metastasis. <br> <br> Synonym: 4T1-A; 4T1.0; 4T1/WT <br> <br><span style="font-size:14px;">B. A. Pulaski and S. Ostrand‐Rosenberg, “Mouse 4T1 Breast Tumor Model,” <em>CP in Immunology</em>, vol. 39, no. 1, Oct. 2000, doi: 10.1002/0471142735.im2002s39.

Shipping Info: Cryopreserved in vials and shipped on dry ice

Disclaimer: For Research Use Only
MorphologyEpithelial-like
Growth ModeAdherent
AgeUnknown
Sex of DonorFemale
Derived From SiteIn situ; Mammary gland
Temperature37°C
Atmosphere5% CO₂
Sterility testingDaily monitoring confirms that the cells are free from bacterial, yeast, and fungal contamination.
Mycoplasma testingNegative for mycoplasma through PCR analysis

Intended Use: This product is intended for laboratory in vitro use only. lt is not intended for diagnostic, therapeutic, or clinical applications.

Disclaimer: Ascent Research endeavors to provide accurate and up-to-date product information. However, no warranties or representations are made regarding its completeness or reliability.

By accepting this product, the customer acknowledges and agrees to assume all risks associated with its receipt, handling, storage, disposal, and use.

This product is provided "AS IS". For Research Use Only. Not for human or animal therapeutic use.