Cancer (Tumor) Cell Lines
Mus musculus (Mouse)
Breast (mammary gland)
Adherent
4T1 is a mouse breast cancer cell line, established from a malignant neoplasm of the mouse mammary gland. The 4T1 cells are tumorigenic and highly metastatic. The transplantable tumor can spontaneously metastasize from the primary site to multiple tissues, including the lymph nodes, blood, liver, lung, brain, and bone. This progressive process of tumor growth and metastatic spread of 4T1 cells closely mimics human breast cancer; therefore, this cell line is regarded as an animal model of stage IV human breast cancer for studying breast cancer progression, immune response, and metastasis.
Synonym: 4T1-A; 4T1.0; 4T1/WT
B. A. Pulaski and S. Ostrand‐Rosenberg, “Mouse 4T1 Breast Tumor Model,” CP in Immunology, vol. 39, no. 1, Oct. 2000, doi: 10.1002/0471142735.im2002s39.
GAA Knockout NCI-H1299 Polyclonal Cells
Cat. No. ARG17624
ARL6IP5 Knockout MES-OV Polyclonal Cells
Cat. No. ARG24229
AVL9 Knockout 786-O Polyclonal Cells
Cat. No. ARG25048
IFT20 Knockout Hela Polyclonal Cells
Cat. No. ARG26030
AKR1B1 Knockout A2780 Polyclonal Cells
Cat. No. ARG28651
ATG9A Knockout HAP1 Polyclonal Cells
Cat. No. ARG27333
Complete description is available upon request.