Cancer (Tumor) Cell Lines
Mus musculus (Mouse)
Breast (mammary gland)
Adherent
4T1 is a mouse breast cancer cell line, established from a malignant neoplasm of the mouse mammary gland. The 4T1 cells are tumorigenic and highly metastatic. The transplantable tumor can spontaneously metastasize from the primary site to multiple tissues, including the lymph nodes, blood, liver, lung, brain, and bone. This progressive process of tumor growth and metastatic spread of 4T1 cells closely mimics human breast cancer; therefore, this cell line is regarded as an animal model of stage IV human breast cancer for studying breast cancer progression, immune response, and metastasis.
Synonym: 4T1-A; 4T1.0; 4T1/WT
B. A. Pulaski and S. Ostrand‐Rosenberg, “Mouse 4T1 Breast Tumor Model,” CP in Immunology, vol. 39, no. 1, Oct. 2000, doi: 10.1002/0471142735.im2002s39.
CAMSAP2 Knockout SK-HEP-1 Polyclonal Cells
Cat. No. ARG32454
PCYOX1L Knockout HT29 Polyclonal Cells
Cat. No. ARG14345
FAM8A1 Knockout Hela Polyclonal Cells
Cat. No. ARG8534
A2M Knockout A549 Polyclonal Cells
Cat. No. ARG32786
MELK Knockout HCT116 Polyclonal Cells
Cat. No. ARG7009
FARP1 Knockout MES-OV Polyclonal Cells
Cat. No. ARG6185
Complete description is available upon request.
