Cat. No. ARP1010
CYNOM-K1 is a skin fibroblast finite cell line derived from a a Cynomologus monkey embryo. Cynomolgus Monkey (Macaca fascicularis) is also commonly known as the long-tailed macaque or crab-eating macaque. In <em>in vitro</em> transformation assay and <em>in vivo</em> tumorigenic evaluation, CYNOM-K1 cells exhibited free of any tumorigenic characteristics. In the test of poliovirus replication, the CYNOM-K1 cell line was permissive to the growth of Sabin poliovirus types 1, 2, and 3, which made it a significant cell model for research and development of poliovirus vaccine. <br> <br> Synonym: Cynom-K1; CYNOMK-1; CYNOMK1; CYNOM-1 <br> <br><span style="font-size:14px">Dotti S, Lombardo T, Villa R, et al. Transformation and Tumorigenicity Testing of Simian Cell Lines and Evaluation of Poliovirus Replication. PLoS One. 2017;12(1):e0169391. Published 2017 Jan 3. doi:10.1371/journal.pone.0169391
| Cell Type | Fibroblast |
| Growth Mode | Adherent |
| Morphology | Fibroblast-like |
| Temperature | 37°C |
| Atmosphere | 5% CO₂ |
| Sterility testing | The bacterial, yeast, and fungi are not detected in these cells by daily monitor. |
| Mycoplasma testing | Negative for mycoplasma through PCR analysis |
Intended Use: This product is intended for laboratory in vitro use only. lt is not intended for diagnostic, therapeutic, or clinical applications.
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