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Human Fibroblast-Like Synoviocytes from Adult Osteoarthritis Donor

Cat. No. ARP1206
Product Type:

Primary Cells

Species:

Homo sapiens (Human)

Tissue Source:

Joint (synovium)

Growth Properties:

Adherent

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Short Description 🔒

Human fibroblast-like synoviocytes (FLS) from adult osteoarthritis donors are freshly isolated from synovial tissue of a donor with arthritic disease. These cells, also known as synovial fibroblasts or type B synoviocytes, are specialized stromal cells that line the synovium and are responsible for producing extracellular matrix components and synovial fluid. In osteoarthritis, FLS exhibit altered phenotypes, including increased production of inflammatory mediators and matrix-degrading enzymes. Therefore, they are widely used as in vitro models to study joint inflammation, cartilage degradation, and the molecular mechanisms underlying osteoarthritis progression.

Product Details
Cell Engineering
Immortalization
Culture Conditions
Quality Control
Disclaimer

Product Details

Product Type:
Primary Cells
Species:
Homo sapiens (Human)
Tissue Source:
Joint (synovium)
Disease:
Arthritic disease
Cell Type:
Stromal cell
Growth Mode:
Adherent
Size/Quantity:
0.5 million
Shipping info:
Cryopreserved in vials and shipped on dry ice
Storage:
Liquid nitrogen (LN2)

Cell Engineering Information

No cell engineering information available.

Immortalization Information

No immortalization information available.

Culture Conditions

Temperature:
37°C
Atmosphere:
5% CO₂

Quality Control

Mycoplasma testing:
Negative for mycoplasma through PCR analysis
Sterility testing:
The bacterial, yeast, and fungi are not detected in these cells by daily monitor.

Disclaimer

Intended Use:
This product is intended for laboratory in vitro use only. It is not intended for diagnostic, therapeutic, or clinical applications.
Disclaimer:
Ascent Research endeavors to provide accurate and up‑to‑date product information. However, no warranties or representations are made regarding its completeness or reliability. References to scientific literature and patents are for informational purposes only, and the customer assumes sole responsibility for verifying their accuracy.

By accepting this product, the customer acknowledges and agrees to assume all risks associated with its receipt, handling, storage, disposal, and use, including compliance with all applicable safety and environmental regulations and precautions. Relevant laws, regulations, and ethical guidelines must be followed in conducting any research, modifications, or derivatives derived from this product.

This product is provided "AS IS", and except as expressly stated herein, Ascent Research disclaims all other warranties, express or implied. Under no circumstances shall Ascent Research, its affiliates, or representatives be liable for indirect, incidental, consequential, or punitive damages arising from the use of this material. While Ascent Research employs rigorous quality control measures, we shall not be held responsible for damages resulting from misidentification or misinterpretation of the provided materials.

Description 🔒

Complete description is available upon request.