Immortalized Cell Line
Kidney
Adherent
M-1 cells are derived from the normal kidney tissue of tg(SV40E)Bri7 transgenic mice and contain integrated SV40 viral DNA. They keep some common characteristics with the cells of the cortical collecting duct (CCD), including typical morphology and expression of CCD-specific antigens. Otherwise, most M-1 cells exhibit features of either intercalated cells or principal cells, the two major cell types of the cortical collecting duct. A subset of 5–10% of the population displays a mixed phenotype, expressing markers of both cell types. When cultured on permeable supports, M-1 cells are capable of forming cavity-like structures and exhibit a measurable negative transepithelial potential difference, indicative of functional polarization.
CPPED1 Knockout A2780 Polyclonal Cells
Cat. No. ARG19117
PANK4 Knockout NCI-H1299 Polyclonal Cells
Cat. No. ARG17782
COPS7B Knockout HT29 Polyclonal Cells
Cat. No. ARG14364
HBB Knockout HAP1 Polyclonal Cells
Cat. No. ARG22459
CASP6 Knockout 769-P Polyclonal Cells
Cat. No. ARG42470
CAPN2 Knockout HEK293T Polyclonal Cells
Cat. No. ARG42192
Complete description is available upon request.