Cancer (Tumor) Cell Lines
Homo sapiens (Human)
Breast (mammary gland)
Adherent
MDA-MB-436 is a human triple-negative breast cancer (TNBC) cell line, which means that it lacks estrogen receptor (ER) and progesterone receptor (PR) expression, as well as HER2 (human epidermal growth factor receptor 2) amplification. MDA-MB-436 cells has mutations in BRCA1 and TP53, which are related to the regulation of DNA repair. This makes MDA-MB-436 a useful tools to investigate BRCA1 and TP53 associated tumorigenesis.
Synonym: MDA_MB_436; MDA MB 436; MDA-Mb-436; MDA-MB436; MDAMB436; MDA-436; MDA436; MB436
ERLIN2 Knockout A2780 Polyclonal Cells
Cat. No. ARG18806
ANXA4 Knockout MES-OV Polyclonal Cells
Cat. No. ARG24161
ICOSLG Knockout NCI-H1299 Polyclonal Cells
Cat. No. ARG30785
HSPB8 Knockout SK-HEP-1 Polyclonal Cells
Cat. No. ARG32628
ACAP1 Knockout Hela Polyclonal Cells
Cat. No. ARG37150
DNAAF9 Knockout HEK293T Polyclonal Cells
Cat. No. ARG39038
Complete description is available upon request.