Cancer (Tumor) Cell Lines
Homo sapiens (Human)
Breast (mammary gland)
Adherent
MDA-MB-436 is a human triple-negative breast cancer (TNBC) cell line, which means that it lacks estrogen receptor (ER) and progesterone receptor (PR) expression, as well as HER2 (human epidermal growth factor receptor 2) amplification. MDA-MB-436 cells has mutations in BRCA1 and TP53, which are related to the regulation of DNA repair. This makes MDA-MB-436 a useful tools to investigate BRCA1 and TP53 associated tumorigenesis.
Synonym: MDA_MB_436; MDA MB 436; MDA-Mb-436; MDA-MB436; MDAMB436; MDA-436; MDA436; MB436
MICALL2 Knockout A549 Polyclonal Cells
Cat. No. ARG10265
ATP11C Knockout HGC-27 Polyclonal Cells
Cat. No. ARG29661
GPAA1 Knockout A2780 Polyclonal Cells
Cat. No. ARG29028
BLM Knockout HCT116 Polyclonal Cells
Cat. No. ARG34763
DSG1 Knockout HAP1 Polyclonal Cells
Cat. No. ARG39819
HCC38
Cat. No. ARC0262
Complete description is available upon request.
