Cancer (Tumor) Cell Lines
Homo sapiens (Human)
Ovary
Adherent
OVTOKO is a human ovarian clear cell adenocarcinoma cell line established from the metastatic tumor of a 78-year-old female who had received CPA chemotherapy. These cells are negative for hormones estrogen (ER) and progesterone (PR) receptors, and tumor-associated antigens (CA19-9, CA125, and TPA) are not detected in OVTOKO cultures. OVTOKO cells express an evaluated level of epidermal growth factor (EGF). When transplanted into mice, OVTOKO cells are capable of forming tumors subcutaneously and in the abdominal cavity, and intraperitoneal injection results in peritoneal spread and distant metastasis. OVTOKO cell line provides a significant experimental cell models to investigate the tumorigenesis and malignant progression of human ovarian clear cell adenocarcinoma.
COL4A2 Knockout A2780 Polyclonal Cells
Cat. No. ARG18634
Hk2 Knockout RAW 264.7 Polyclonal Cells
Cat. No. ARG23554
BAZ1A Knockout MES-OV Polyclonal Cells
Cat. No. ARG24311
ITPKC Knockout Hela Polyclonal Cells
Cat. No. ARG26304
AGPAT5 Knockout HAP1 Polyclonal Cells
Cat. No. ARG27231
NLRC5 Knockout 786O Polyclonal Cells
Cat. No. ARG5168
Complete description is available upon request.