Cancer (Tumor) Cell Lines
Homo sapiens (Human)
Blood (peripheral blood)
Suspension
The BJAB cell line is a human Burkitt lymphoma cell line (B cell orgin), derived from the inguinal tumor of a 5-year-old African girl. It is an Epstein-Barr virus (EBV)-negative lymphoblastoid cell line that does not harbor EBV genome or express EBV specified antigen EBNA, but these cells carry surface-bound immunoglobulin. BJAB grows in suspension with a round to polymorphic morphology. The cells rapidly lose viability when approaching maximal culture density; therefore, over-dense cultures should be avoided.
BJAB has wide applications in molecular mechanism and cancer research. Their stable EBV status allows for a valuable application in research on EBV transformation or infection of B cells, enabling researchers to investigate the effect of EBV virus contributing to lymphomagenesis. Otherwise, the BJAB cells exhibit features of Burkitt lymphoma, making it a cell model for genetic and phenotypic studies. The BJAB cell line also serves as a cell model of EBV-negative Burkitt lymphoma in biomedical research for evaluating cytotoxic activity in comparison with EBV-positive counterparts.
Synonyms: BJAb; BJA-B; BJAB-1; BJA-B1; BJA-B-1
PHKA1 Knockout A2780 Polyclonal Cells
Cat. No. ARG19181
KLF9 Knockout HAP1 Polyclonal Cells
Cat. No. ARG23029
IREB2 Knockout SK-HEP-1 Polyclonal Cells
Cat. No. ARG32689
CD320 Knockout HEK293T Polyclonal Cells
Cat. No. ARG43509
DLGAP4 Knockout AGS Polyclonal Cells
Cat. No. ARG38913
IRF1 Knockout Ramos Cell Line
Cat. No. ARG0696
Complete description is available upon request.
