Cat. No. ARC1033
Mono-Mac-6 is a human monocytic cell line derived from peripheral blood of a patient with Acute monoblastic leukemia (AML, M5). Once isolated, these cells showed characteristics of monocytic cell line on the basis of morphology, cytochemical and immunological criteria. Mono-Mac-6 cells resemble mature monocytes more closely than other monocytic cell lines, like THP-1 and U937. Cultured in vitro, Mono-Mac-6 are round cells growing in small clusters and in suspension. They are widely used in study of monocyte differentiation and activation, research on cytokine production and immune signaling, such as LPS response and TLR pathway. <br> <br>Synonym: MonoMac 6; MM-6; MM6; MonoMac-6
| Cell Type | Monocyte cell line |
| Sex of Donor | Male |
| Age | 64 years |
| Derived From Site | In situ; Peripheral blood |
| Growth Mode | Suspension |
| Morphology | Round/multiformed cells |
| Temperature | 37°C |
| Atmosphere | 5% CO₂ |
| Sterility testing | The bacterial, yeast, and fungi are not detected in these cells by daily monitor. |
| Mycoplasma testing | Negative for mycoplasma through PCR analysis |
Intended Use: This product is intended for laboratory in vitro use only. lt is not intended for diagnostic, therapeutic, or clinical applications.
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