Immune & Lymphatic System

The immune system is the defense system in the body to protect the body from infections, injuries, and disease. It recognizes invading pathogens (such as bacteria, viruses, fungi, parasites, and cancer cells), limits their activities, eliminates them, and supports tissue repair. The immune system consists of organs/tissues (such as spleen, tonsils, thymus, bone marrow, skin, mucosa, lymph node), proteins (antibodies and cytokines), white blood cells (leukocytes), and the complement system. The lymphatic system is a vital part of immune system. It supports immune system by transporting immune cells, filtering pathogens, and facilitating immune responses throughout the body. Specialized cells such as human lymphatic endothelial cells play essential roles in lymphatic vessel function and immune regulation.

Cells in immune system and lymphatic system are used to promote the advanced research in immunology, inflammation, oncology, autoimmunity, infectious disease, and cell therapy development. We provide a comprehensive range of primary immune cells and blood-derived products, including:
1. Peripheral blood mononuclear cells (PBMCs) from different species or different disease state, such as human peripheral blood mononuclear cells (human PBMCs), mouse PBMCs, dog PBMCs (canine PBMCs), SLE PBMCs.
2. Lymphoid lineage cells (lymphocytes) – B cells, T cells lineage (immune T cells, CD3 T cells, T reg cells, Th17 cells, murine T cells), and NK cells.
3. Myeloid lineage cells – monocytes lineage (human monocytes, human dendritic cells, mouse dendritic cells, human macrophages, mouse macrophage, rat macrophages, bone marrow derived macrophages), adrenal mast cells, platelets, and granulocytes (human neutrophil cells).
4. Hematopoietic and tissue-derived immune materials such as, human CD34 cells, human and mouse spleen cells (including human splenocytes and mouse splenocytes), chicken red blood cells, and rabbit red blood cells.

These immune and blood cell products support applications in immuno-oncology, vaccine development, autoimmune disease research, transplantation, and translational immunology.