Female Reproductive System

The Female Reproductive System category provides cells for studying ovarian function, uterine biology, breast health, implantation, and placentation. Endometrial epithelial cells line the uterus and are involved in menstruation, implantation, and endometrial regeneration; they are used for studies on endometriosis, endometrial cancer, and fertility. Fallopian tube epithelial cells are the origin of many high-grade serous ovarian cancers; they are used for early detection research and studies on tubal ligation effects. Placental cells are important for pregnancy research, including studies on preeclampsia, intrauterine growth restriction, and maternal-fetal interface. Mammary epithelial cells are the functional cells of the breast; they line the ducts and lobules and are used for lactation studies, breast development, and cancer research. Granulosa cells surround the oocyte and produce estrogen and progesterone; they are used for folliculogenesis studies, polycystic ovary syndrome (PCOS), and in vitro fertilization research. Theca cells produce androstenedione as substrate for estrogen synthesis; they are used for studies on androgen excess in PCOS. Luteal cells form the corpus luteum and produce progesterone; they are used for studies on luteal phase defects and early pregnancy maintenance. Vaginal epithelial cells are used for mucosal immunology, microbicide testing, and studies on bacterial vaginosis and yeast infections. Vulvar fibroblasts support the external genitalia and are used for wound healing and lichen sclerosus studies. Myometrial smooth muscle cells are responsible for uterine contractions during labor; they are used for studies on preterm labor, dysmenorrhea, and uterine fibroids. Uterine fibroblasts are used for fibrosis and endometriosis models, including studies on extracellular matrix remodeling. Oocyte cumulus cells are the supporting cells around the oocyte; they are used for studies on oocyte maturation, fertilization, and embryo quality in assisted reproduction.

Our female reproductive cells, including ovarian cells and endometrial cells, are tested for mycoplasma. Granulosa cells and theca cells can be co-cultured for follicle development studies, including FSH and LH responsiveness. Placental cells model the maternal-fetal interface, including studies on nutrient transport and immune tolerance. Fallopian tube epithelial cells are used for early detection research on high-grade serous ovarian cancer, with markers like PAX8 and WT1. Myometrial smooth muscle cells are used for contractility assays in preterm labor research, measuring calcium flux and oxytocin response. Whether you need oocyte cumulus cells for IVF studies or vaginal epithelial cells for microbiome research, our Female Reproductive System category supports your gynecology and reproductive biology from basic science to clinical translation.